Open access Corresponding author: Hanaa H El-Sayed Email: Hanaa_Hamad2003@Yahoo.com Received: 16 May 2025 Accepted: 28 June 2025 Publication: 7 July 2025 Citation El-Sayed HH and Abd-Elrady SA (2025): Plant Stem Cells: Regulatory Mechanisms and Biotechnological Applications. BNNI;127-137 Doi: Plant stem cells play a central role in lifelong organogenesis, growth, and regeneration by balancing self-renewal and differentiation. These pluripotent cells reside in key meristematic regions, the shoot apical meristem (SAM), root apical meristem (RAM), and lateral meristems, each governed by intricate genetic, hormonal, and epigenetic controls. Over the past two decades, substantial progress has been made in elucidating the molecular networks that sustain stem cell identity and regulate pattern formation and organ initiation. Core pathways involving transcription factors such as WUSCHEL (WUS), CLAVATA (CLV), and PLETHORA (PLT), in conjunction with phytohormonal signaling and chromatin dynamics, orchestrate stem cell function. This review synthesizes current insights into the spatial organization and molecular control of plant stem cells, explores recent advances in genetic and imaging technologies, and examines their translational potential in biotechnology and crop improvement. Finally, it highlights current knowledge gaps and outlines future research directions to deepen our understanding of plant developmental plasticity and regenerative capacity.
Elsayed, H., & Abd-Already, S. (2025). Review literature. Plant Stem Cells: Regulatory Mechanisms and Biotechnological Applications. Bulletin of the National Nutrition Institute of the Arab Republic of Egypt, 65(1), 127-137. doi: 10.21608/bnni.2025.440498
MLA
Hanaa H Elsayed; Seham A Abd-Already. "Review literature. Plant Stem Cells: Regulatory Mechanisms and Biotechnological Applications", Bulletin of the National Nutrition Institute of the Arab Republic of Egypt, 65, 1, 2025, 127-137. doi: 10.21608/bnni.2025.440498
HARVARD
Elsayed, H., Abd-Already, S. (2025). 'Review literature. Plant Stem Cells: Regulatory Mechanisms and Biotechnological Applications', Bulletin of the National Nutrition Institute of the Arab Republic of Egypt, 65(1), pp. 127-137. doi: 10.21608/bnni.2025.440498
VANCOUVER
Elsayed, H., Abd-Already, S. Review literature. Plant Stem Cells: Regulatory Mechanisms and Biotechnological Applications. Bulletin of the National Nutrition Institute of the Arab Republic of Egypt, 2025; 65(1): 127-137. doi: 10.21608/bnni.2025.440498
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