Effect of Feeding Peanut and Sesame Seeds on Bone of Rats Suffering from Osteoporosis

Document Type : Original Article


Faculty of Specific Education, Ain Shams University, Cairo, Egypt


This study was carried out to determine the effect of two levels of peanut seeds (Arachis hypogaea) and sesame seeds (S. indicum) on rats suffering from osteoporosis. Forty eight female rats weighting an average of (200±10g) were used in this study. The rats were divided into two main groups. The first main group (6 rats) fed on basal diet as a (negative control group). The second main group (42 rats) received oral prednisone acetate (Glucocorticoid)(GC) daily for two weeks to induce osteoporosis, then the second main group divided into seven subgroups as follows: The first subgroup (6 rats) fed on basal diet as a (positive control group), the second and third subgroups fed on basal diet containing (5% and 10%) peanut seeds , respectively. The fourth and fifth subgroups fed on diet containing (5% and 10%) sesame seeds. The sixth and seventh subgroups fed on diet containing (5% and 10%) combination of Sesame and Peanut seeds. Sesame and peanut were added instead of corn starch. The results revealed that peanut seeds, sesame seeds, and combination especially 10% improved the nutritional status, the kidney functions (uric acid, urea nitrogen and creatinine), level of calcium and phosphorus; femur bone calcium and femur bone phosphorus and bone mineral density (BMD), Bone Mineral Concentration (BMC) compared to the positive group. The study recommends eating (peanut, sesame) seeds and food rich in calcium that help in accelerating bone growth and decrease bone fracture incidence.