Protective Role of Bovine Liver and Tomato Powder Against Negative Effects of Flummox Antibiotic in Rats

Authors

1 Growth and Nutrient Requirements Department, National Nutrition Institute (NNI), Egypt

2 Clinical Nutrition Department, National Hepatology and Tropical medicine research Institute, Egypt.

3 National Heart Institute, Giza, Egypt

Abstract

This research sought to determine whether interactions between rat diet and the biological and metabolic responses could mitigate the side effects of the antibiotic Flummox. The addition of tomato powder that had been cooked, dried, and ground, along with 10% of lyophilized bovine liver. Out of 44 mature male rats, four main categories were developed. As a negative control, the first set only received regular meals. The third group received lyophilized bovine liver, the fourth group received tomato powder, and the second group received a fundamental diet together with Flumox as a positive control. In comparison to the Flumox group, the liver and tomato-treated groups displayed significantly lower levels of liver enzymes (ALT, AST, and ALP), kidney functions, lymphocytes, leukocytes, and oxidative stress, as well as significantly higher levels of red blood cells hemoglobin and glutathione (GSH) in the hepatic and renal tissues. One can conclude that combining some nutrients (liver, tomato) can reduce the amount of excess weight in rats and treat the many physiological and hematological aberrations caused by oxidative stress diseases connected with antibiotics.

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