The National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Effect of Feeding Cake Fortified with Different Concentrations of Ashwagandha Root against Sodium Arsenite Toxicity in Male RatsEffect of Feeding Cake Fortified with Different Concentrations of Ashwagandha Root against Sodium Arsenite Toxicity in Male Rats122421510.21608/bnni.2016.4215ENSamah A. ElsemelawyElsemelawyHome Economics Dept., Faculty of Specific Education, Tanta University .EgyptRehabTag Al DeenHome Economics Dept., Faculty of Specific Education, Zagazig University, EgyptJournal Article20171119In ayurvedic medicine, herbal plants as ashwagandha (Withania somnifera) were used as a powerful plant to cure many of diseases. The present study was carried out to evaluate the protective effect of fortified cake by different concentrations of ashwagandha root powder against sodium arsenite induced toxicity in rats. Thirty male Sprague-Dawley rats weighing (120 ± 10g).Rats classified into to five groups (6 rats). The first group was kept as a negative control and fed on the basal diet only. Other four groups were administered sodium arsenite at a single dose of 5 mg/kg/day to induce toxicity injury. One of these groups left as positive control (group 2). The third group was treated with 100% wheat flour fortified cake. The fourth group was treated with 10 % ashwagandha powder fortified cake. The fifth group was treated with 20 % ashwagandha powder fortified cake. Laboratory analysis showed that fortification with ashwagandha inhibited the levels of liver injury biomarkers, also improved the kidney function enzymes. These results suggested that ashwagandha has a powerful antioxidant effect which can reduce organ injury through its ability by scavenge the free radical.https://bnni.journals.ekb.eg/article_4215_349229d70f36bd0737cc59058010949d.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Effect of Ginseng (Panax ginseng) against Testicular Toxicity Induced by Sodium Valproate in Male RatsEffect of Ginseng (Panax ginseng) against Testicular Toxicity Induced by Sodium Valproate in Male Rats125421610.21608/bnni.2016.4216ENLobnaShelbayaDepartment of Home Economics, Faculty of Specific Education, Mansoura University, EgyptJournal Article20171119The aim of this experimental study was to investigate the effects of ginseng powder, extract, L-carnitine and their combination against sodium valproate induced testicular toxicity in rats, the reproductive performance of male rats with respect to semen parameters, male sex hormones and the testicular antioxidant system. A total of forty two mature male albino rats were divided into six groups of seven rats. The control group received saline, whereas the other five groups received sodium valproate the firs represented positive group, after that four groups received ginseng (100 mg/kg. diet), ginseng extract (10 mg/kg. B wt /rat), L-carnitine (150 mg/kg Bwt/rat /day) or a combination of both ginseng and L-carnitine via a stomach tube daily respectively for one month. At the end of the treatment period, rats were sacrificed, weights of sexual organ recorded and their sperm characteristics count, antioxidant enzyme factors levels (reduced glutathione, malondialdehyde, superoxide dismutase and total antioxidant capacity) and sex hormone levels (testosterone, Follicle stimulating hormone (FSH) and luteinizing hormone (LH) were analyzed. Results showed that the four experimental treatments improved lipid parameters, liver function, sperm parameters, antioxidant enzyme activity and testosterone hormone levels; the most pronounced positive effects were observed in the group that received a combination of both ginseng and L-carnitine. Therefore, the administration of a combination of ginseng and L-carnitine may be beneficial for improving male sexual performance.https://bnni.journals.ekb.eg/article_4216_12169e06ed0c875beb412ebff8ae29da.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Amelioration of Cisplatin Induced Sexual Toxicity on Male Rats by Using Fortified of Flat Bread with Moringa Oleifera129421710.21608/bnni.2016.4217ENAliAl ShammariFaculty of Home Economics, the Public Authority for Applied Education and Training, KuwaitHanaaEl-MehiryDepartment of Home Economics, Faculty of Specific Education, Mansoura University, EgyptJournal Article20171119The study aim to investigat the effect of fortification of flat bread with moringa oleifera aganist cisplatin induced sexual toxicity in male rats and evaluates the sensory characteristics and the nutritive value of the fortified bread prepared against cisplatin. Chemical composition of flat bread, flat bread fortified by moringa powder and oil were determined. To induce sexual toxicity, male rats were given cisplatin by (12 mg/kg body weight). Thirty five male rats were classified into seven groups (n=5). The first group was kept as negative control group, while the other six groups were injected with cisplatin to induce toxicity in various experimental animals; one of those groups was fed on basal diet only and served as positive control group (G2). The third group (G3) was fed on basal diet and treated with control flat bread (100% wheat flour). The fourth and fifth (G4&G5) groups were fed on basal diet containing fortified flat bread with 10% & 15% moringa powder respectively. The sixth and seventh (G6&G7) were fed on basal diet containing fortified flat bread with 5 ml and 10 ml moringa oil respectively. Results: The results revealed that rats consumed fortified flat bread with moringa powder and oil showed significant increases in follicle stimulating hormone level (FSH), and luteinizing hormone (LH), compared with the positive control. Administration of moringa powder and oil improved kidney function, liver enzymes and antioxidant parameters in male rats. In the current study, the protective effect of moringa powder and oil against cisplatin induced sexual toxicity in rats was improved. Conclusions: Moringa powder and oil may be used to prevent toxicity during chemotherapeutic treatment with cisplatin.https://bnni.journals.ekb.eg/article_4217_9d00b39775f22956aca2ff044ebaa576.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Effect of Different Extraction Methods on Stablity of Anthocyanins Extracted from Red Onion peels (Allium cepa) and Its Uses as Food Colorants124421810.21608/bnni.2016.4218ENOm-HashemAliFood health Dept., National Nutrition Institute, Cairo, EgyptHananAl-sayedFood Science Dept., Fac. of Agriculture, Ain Shams Univ., Cairo, EgyptNessrienYasinFood Science Dept., Fac. of Agriculture, Ain Shams Univ., Cairo, EgyptEffatAfifiFood health Dept., National Nutrition Institute, Cairo, EgyptJournal Article20171119he present work was carried out to produce a natural red color (anthocyanins) from red onion peels (Allium cepa) by four different solvent for coloring some food product. The results showed that acidified ethanol (0.01%Hcl) had the greatest efficient in extracting red onion peels anthocyanins followed by acidified methanol (0.01% Hcl), while acidified distilled water (0.01%) and distilled water are the less effective. At low pH(2.0and3.0),natural anthocyanins extracts exhibited their greatest stabilities. Red onion peels anthocyanins extracts by acidified methanol was heated for 30 min at temperatures of 40, 60, 80 and 100◦c retained 99.16, 98.79, 91.56 and 69.45 %, respectively. The highest stability of anthocyanins extracted by both of acidified methanol and ethanol was at 40 to 80◦c until holding time reached to 60 min. Color and overall acceptability of hard candy containing 0.3% natural anthocyanins extracted from red onion peels by acidified methanol recorder highly score with synthetic color (Allure).On the other hand, glazing jelly containing 0.25% natural anthocyanins extracted from red onion peels by all solvents recorded closely score with synthetic color.https://bnni.journals.ekb.eg/article_4218_fe31a1852a7b8a00889d480e29b6d268.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Effect of Feeding Peanut and Sesame Seeds on Bone of Rats Suffering from Osteoporosis119422010.21608/bnni.2016.4220ENNagibeWilsonFaculty of Specific Education, Ain Shams University, Cairo, EgyptJournal Article20171119This study was carried out to determine the effect of two levels of peanut seeds (Arachis hypogaea) and sesame seeds (S. indicum) on rats suffering from osteoporosis. Forty eight female rats weighting an average of (200±10g) were used in this study. The rats were divided into two main groups. The first main group (6 rats) fed on basal diet as a (negative control group). The second main group (42 rats) received oral prednisone acetate (Glucocorticoid)(GC) daily for two weeks to induce osteoporosis, then the second main group divided into seven subgroups as follows: The first subgroup (6 rats) fed on basal diet as a (positive control group), the second and third subgroups fed on basal diet containing (5% and 10%) peanut seeds , respectively. The fourth and fifth subgroups fed on diet containing (5% and 10%) sesame seeds. The sixth and seventh subgroups fed on diet containing (5% and 10%) combination of Sesame and Peanut seeds. Sesame and peanut were added instead of corn starch. The results revealed that peanut seeds, sesame seeds, and combination especially 10% improved the nutritional status, the kidney functions (uric acid, urea nitrogen and creatinine), level of calcium and phosphorus; femur bone calcium and femur bone phosphorus and bone mineral density (BMD), Bone Mineral Concentration (BMC) compared to the positive group. The study recommends eating (peanut, sesame) seeds and food rich in calcium that help in accelerating bone growth and decrease bone fracture incidence.https://bnni.journals.ekb.eg/article_4220_812693227b23c4aa77611ab5fed2306c.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Technological properties and acceptability of spaghetti supplemented with orange peels powder or barley flour122422110.21608/bnni.2016.4221ENMahmoud S. HassanHassanFood Sci. Dept., Fac. of Agric., Cairo UniversityMohamedAlyFood Sci. Dept., Fac. of Agric., Cairo UniversityMahmoudBekheetFood Sci. Dept., Fac. of Agric., Cairo UniversityJournal Article20171119The quality attributes of spaghetti that produced from semolina and spaghetti with different levels of barley flour or orange peels powder as a dietary fiber sources were studied. Three levels of barley flour were used (15 %, 30 % and 45 %) and three levels of orange peels powder were used (5 %, 10 % and 15 %). Chemical composition, farinograph test, cooking quality parameters and sensory evaluation were determined. . The results indicated that increasing the level of barley flour or orange peels powder cause an increase in dietary fiber and ash content and decrease in calories. Cooking quality parameters were also decreased with increasing the level of barley flour or orange peels powder except swelling index which increased. Semolina could be replaced by barley flour at levels up to 45 % and orange peels powder at level of 5 % to produce spaghetti having good characteristics and not significantly different from control for most of the evaluated sensory characteristics. Spaghetti contained 15 % of barley flour could be considered a source of dietary fiber, while other treatments (30 and 45 % of barley flour or 5, 10 and 15 % of orange peels powder) represent food high in dietary fiber according to codex Alimentarius (2009).https://bnni.journals.ekb.eg/article_4221_fdca66f73c1247d25909b43d765aeffb.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Antidiabetic and Antiatherosclerotic activity of dried red radish roots (Raphanus sativus L) on hypercholesterolemic diabetic rats131422210.21608/bnni.2016.4222ENAbeerKhedrDep. of Nutrition & Food Science, Faculty of Home Economics, Menoufia UniversityNaglaaEl SheikhDep. of Nutrition & Food Science, Faculty of Home Economics, Menoufia UniversityJournal Article20171119This study was performed to assess the hypoglycemic and Antiatherosclerotic effects of dried red radish roots on hypercholesterolemic diabetic rats. Red radish roots contained good quantities of bioactive compounds as phenolic compounds, flavonoids and anthocyanin also its antioxidant activity. Rats were randomly divided into two main groups, the first group is normal control, and the second is the hypercholesterolemic diabetic rats which were divided into four subgroups (8 rats each) as follow: subgroup 1 served as positive control group, subgroup 2, 3 and 4 were fed on the diet containing 2.5%, 5% and 7.5% of dried red radish roots powder for 6 weeks respectively. After completing the treatment period, blood samples were collected for used to the biochemical analysis as blood glucose, insulin and lipid profile. Heart were taken for aortic histopathological. The results indicated that treatments with dried red radish roots significantly decreased the levels of blood and urine glucose, lipid profile, hepatic lipid and atherogenic indices compared to positive control group and improved the level of insulin and histopathological changes in the aorta of hypercholesterolemic diabetic rats. In conclusion, red radish roots as a source of antioxidant compounds had hypoglycemic effect, improved lipid metabolism and prevent cardiovascular diseases.https://bnni.journals.ekb.eg/article_4222_e7f0a48908c151e305493a80375eb845.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Physiological effect Of Selenium& Green treatment on Cisplatin-induced Nephrotoxicity in Rats122422310.21608/bnni.2016.4223ENHewaidaFadelDepartment of Nutritional Chemistry& Metabolism, National Nutrition `InstituteJournal Article20171119The present study was a trial to investigate the physiological effect of Selenium& Green tea as natural antioxidant on cisplatin- induced nephrotoxicity in rates. Thirty two adult male albino rats (Sprague – Dawley) were divided into two main groups. First group: 8 rats were fed on standard diet (S.D.), as a negative control group. Second group: 24 rats were injected with a single dose of Cisplatin (CP) for inducing nephrotoxicity (2.5 mg/Kg BW) then it was divided to three subgroups (8 rats/ subgroup). Subgroup (1): fed on (S.D.) as a positive control group (nephrotoxic group). Subgroup (2): fed on (S.D.) + Selenium (0.6 mg/Kg BW/day).Subgroup (3): fed on (S.D.) +Green Tea (100 mg /kg BW/day). The experimental period was four weeks. The results proved that selenium& green tea groups showed significant increase in body weight gain (BWG) and food efficiency ratio (FER) when compared with nephrotoxic group. Rats treated with Selenium and Green tea showed significant increase in antioxidant level: serum vitamin E & kidney glutathione when compared with nephrotoxic group. The results showed that Selenium and Green tea groups showed significant reduction in kidney function indices: serum urea, creatinine, uric acid, nitric oxide and serum sodium in compared with nephrotoxic group. Best results in histopathological examination of kidney were in Selenium group. Conclusion: These results suggest that the use of selenium& green tea could be beneficial in improving kidney functions in nephrotoxic rats, through a significant decrease in peroxidative levels and increase in antioxidant status.https://bnni.journals.ekb.eg/article_4223_5266cb82a9988ac22dece9f64ee4d05b.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101ASSESSMENT OF THE STATIC POSTURE DURING STANDING IN OBESE ADOLESCENT GIRLS117422410.21608/bnni.2016.4224ENLobnaEl-HadidyNational Nutrition InstituteEmanEl-HadidyFaculty of Physical Therapy, Cairo UniversityAmiraAbo El EzzMisr University for Science and TechnologyJournal Article20171119Obesity is significantly associated with an endless list of postural disorders. The prevalence of childhood obesity is steadly increasing so it is important to study the effect of obesity on musculoskeletal system on these children to provide meaningful support in prevention and their treatment. Aim of the study: the study aims to assess the static posture during standing position among the obese adolescent girls and compare their obtained data with non-obese adolescent girls. Cases and Methods: One hundred of non-obese adolescent girls ( group A) compared with thirty obese adolescent girls ( group B ). Their ages ranged from 12-14 years old, the mean values + SD were 13+0.7 and 12.8+1.2 years old for both groups respectively. All participated girlwere evaluated when they were on static standing position from sagittal view using photography. AutoCAD (Computer Aided Design) was used to analyze the photographic posture. The posture measurements was achieved through analysis of five angles (cervico-thoracic angle, trunk angle, lumber angle, pelvic tilt angle, sway angle ) to quantitatively assess the positioning of several body segments in the upright . Results : The results of this study revealed significant differences when comparing the mean values of the measuring angles between obese adolescent girls and non-obese adolescent girls. Conclusion: Obesity may have a greater effect on static posture. These effects on obese adolescent girlswere represented by protruded head , hyper kyphosis (dorsal spine), hyper lordosis (lumber spine ), anterior pelvic tilting , and increased posture sway .https://bnni.journals.ekb.eg/article_4224_3cbc129474c7a313fbe854b0b70b169c.pdfThe National Nutrition InstituteBulletin of the National Nutrition Institute of the Arab Republic of Egypt1110-097447220161101Effects of Feeding Some Herbs on Hyperuricemic Rats130422510.21608/bnni.2016.4225ENWalaaAniessHome Economic Dept., Fac. of Specific Education, Ain-shams UniverJournal Article20171119Gout is an inflammatory joint disorder characterized by hyperuricaemia and precipitation of monosodium urate crystals in the joints. This study aimed to discover the beneficial effects of feeding cinnamon or /and ginger, as a powder form, on the consequence symptoms of gout on induced hyperuricemic rats. Forty nine male albino rats weighing 192 ±23g were divided into 7 equal groups; negative control group fed on standard diet only, while the other 6 experimental groups were injected orally with ethanol (1.8g per kilogram of body weight) every 24 hour for eight days to induce hyperuricemia,<br />after confirmation they fed on standard diet only (positive control) or with adding 1% & 2% ginger, 1% & 2% cinnamon and mixture of 1% ginger + 1% cinnamon of total diet weight for continued four weeks after adaptation period.<br />Serum uric acid, urea and creatinine, serum liver enzymes (AST, ALT, and ALP) activities, total protein, serum albumin and globulin levels were determined. Results revealed that supplementations with ginger, cinnamon or their mixture for<br />hyperuricemic rats diets; declined the feed efficiency ratios, while increased relative weight of liver and kidneys significantly (p<0.05) ameliorated proportionally with the level of adding, also increments of uric acid, urea and creatinine levels were decreased significantly, furthermore decreased the raised serum levels of ALT, AST & ALP enzymes’ activities and ameliorated significantly the documented decrements in the levels of serum total proteins and albumin comparing with positive control group. Histopathological kidneys’ investigation revealed that higher supplementations with 2% ginger, cinnamon or their mixture groups modulate all undesirable changes recorded in kidneys of positive control group. These outcomes could mention that using ginger and cinnamon may improve kidney functions, liver enzymes and protein fractions, especially the mixture of them which was the most beneficial effects recorded; it could be used as hypouricemic agent and adjuvant treatment for gout disease.https://bnni.journals.ekb.eg/article_4225_40596d78be9124eb18b3ba1bff43c976.pdf